Cancer is the primary cause of death for Europeans under 65. In the EU, cancer accounts for more deaths in people under 65 than any other disease. It hosts less than 10% of the world’s population, but yet has 23% of all cancer cases. On average, only 1 in 2 cancer patients survive and one in two of us will face cancer in our lifetimes. A successful fight against cancer relies upon identifying, aligning, planning and coordinating actions of these initiatives at the Scientific and Technical level. A task that needs to be done by a neutral, independent, yet competent entity – the JRC. It is in this context that the JRC is establishing the EC Knowledge Centre on Cancer (KCC).